Angeliki P Kourounakis : rechercher sur Z-Library

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1

Synthesis and pharmacological evaluation of novel derivatives of anti-inflammatory drugs with increased antioxidant and anti-inflammatory activities

Angeliki P. Kourounakis, Dimitrios Galanakis, Karyofillis Tsiakitzis, Eleni A. Rekka, Panos N. Kourounakis

Journal:

Drug Development Research

Année:

1999

Langue:

english

Fichier:

PDF, 186 KB

english, 1999

2

Anti-inflammatory Properties of New Adamantane Derivatives. Design, Synthesis, and Biological Evaluation

Ekaterini Antoniadou-Vyza, Nikos Avramidis, Angeliki Kourounakis, Lygeri Hadjipetrou

Journal:

Archiv der Pharmazie

Année:

1998

Langue:

english

Fichier:

PDF, 115 KB

english, 1998

3

Design of more potent squalene synthase inhibitors with multiple activities

Angeliki P. Kourounakis, Alexios N. Matralis, Anastasios Nikitakis

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2010

4

QSAR of substituted morpholines with antioxidant and squalene synthase inhibitory activity

Anastasios Nikitakis, Angeliki P. Kourounakis

Journal:

Medicinal Chemistry Research

Année:

2011

Langue:

english

Fichier:

PDF, 362 KB

english, 2011

5

Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

Rianne A F De Ligt, Angeliki P Kourounakis, Ad P IJzerman

Journal:

British Journal of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 196 KB

english, 2000

6

Antinociceptive Properties of 1,8-Cineole and β-Pinene, from the Essential Oil of Eucalyptus camaldulensis Leaves, in Rodents

Liapi, Charis, Anifantis, Georgios, Chinou, Ioanna, Kourounakis, Angeliki, Theodosopoulos, Stelios, Galanopoulou, Panagiota

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

7

Morpholine as a privileged structure: A review on the medicinal chemistry and pharmacological activity of morpholine containing bioactive molecules

Kourounakis, Angeliki P., Xanthopoulos, Dimitrios, Tzara, Ariadni

Journal:

Medicinal Research Reviews

Année:

2019

Langue:

english

Fichier:

PDF, 3.80 MB

english, 2019

8

Elucidation of structure–activity relationships of 2-amino-3-benzoylthiophenes: Study of their allosteric enhancing vs. antagonistic activity on adenosine A1 receptors

Angeliki P. Kourounakis, Pieter A.M. Van der Klein, Ad P. Ijzerman

Journal:

Drug Development Research

Année:

2000

Langue:

english

Fichier:

PDF, 243 KB

english, 2000

9

Alkannin and Shikonin: Effect on Free Radical Processes and on Inflammation - A Preliminary Pharmacochemical Investigation

Angeliki P. Kourounakis, Andreana N. Assimopoulou, Vassilios P. Papageorgiou, Antonis Gavalas, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Année:

2002

Langue:

english

Fichier:

PDF, 99 KB

english, 2002

10

Effect of Guaiazulene on Some Cytochrome P450 Activities. Implication in the Metabolic Activation and Hepatotoxicity of Paracetamol

Angeliki P. Kourounakis, Eleni A. Rekka, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Année:

1997

Langue:

english

Fichier:

PDF, 499 KB

english, 1997

11

Stress and Active Oxygen Species – Effect of α-Tocopherol on Stress Response

Karyofyllis Tsiakitzis, Angeliki P. Kourounakis, Ekaterini Tani, Eleni A. Rekka, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Année:

2005

Langue:

english

Fichier:

PDF, 102 KB

english, 2005

12

Antioxidant Activity of Newly Synthesized 2,7-Diazaphenothiazines

Beata Morak-Młodawska, Krystian Pluta, Alexios N. Matralis, Angeliki P. Kourounakis

Journal:

Archiv der Pharmazie

Année:

2010

Langue:

english

Fichier:

PDF, 542 KB

english, 2010

13

ChemInform Abstract: Allosteric Modulation of G Protein-Coupled Receptors

Ad Ijzerman, Angeliki Kourounakis, Pieter van der Klein

Journal:

Année:

2001

Fichier:

PDF, 25 KB

2001

14

Synthesis of New Azulene Derivatives and Study of Their Effect on Lipid Peroxidation and Lipoxygenase Activity.

Eleni Rekka, Michael Chrysselis, Ioanna Siskou, Angeliki Kourounakis

Journal:

Année:

2003

Fichier:

PDF, 140 KB

2003

15

Synthesis and Activity on Free Radical Processes and Inflammation of 9,10-Dihydro-5,8-dimethoxy-triptycene-quinones.

Nikoletta J. Xanthopoulou, Angeliki P. Kourounakis, Spyros Spyroudis, Panos N. Kourounakis

Journal:

Année:

2003

Fichier:

PDF, 125 KB

2003

16

Synthesis and Pharmacological Evaluation of Amide Conjugates of NSAIDs with L-Cysteine Ethyl Ester, Combining Potent Antiinflammatory and Antioxidant Properties with Significantly Reduced Gastrointestinal Toxicity.

Dimitrios Galanakis, Angeliki P. Kourounakis, Karyophyllis C. Tsiakitzis, Christos Doulgkeris, Eleni A. Rekka, Antonios Gavalas, Constantina Kravaritou, Christos Charitos, Panos N. Kourounakis

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 13 KB

english, 2004

17

Allosteric modulation of the rat adenosine A1 receptor: Differential effects on agonist and antagonist binding

Angeliki P. Kourounakis, Corine Visser, Miriam de Groote, Ad P. IJzerman

Journal:

Drug Development Research

Année:

2000

Langue:

english

Fichier:

PDF, 156 KB

english, 2000

18

Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias

Maria Koufaki, Anastasia Detsi, Elissavet Theodorou, Christina Kiziridi, Theodora Calogeropoulou, Athanasios Vassilopoulos, Angeliki P. Kourounakis, Eleni Rekka, Panos N. Kourounakis, Catherine Gaitan

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 305 KB

english, 2004

19

Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties

Ioanna C. Siskou, Eleni A. Rekka, Angeliki P. Kourounakis, Michael C. Chrysselis, Kariofyllis Tsiakitzis, Panos N. Kourounakis

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 243 KB

english, 2007

20

Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity

Dimitrios Galanakis, Angeliki P Kourounakis, Karyophyllis C Tsiakitzis, Christos Doulgkeris, Eleni A Rekka, Antonios Gavalas, Constantina Kravaritou, Christos Charitos, Panos N Kourounakis

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 255 KB

english, 2004

21

Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties

Christos M. Doulgkeris, Dimitrios Galanakis, Angeliki P. Kourounakis, Karyofyllis C. Tsiakitzis, Antonios M. Gavalas, Phaedra T. Eleftheriou, Panagiotis Victoratos, Eleni A. Rekka, Panos N. Kourounaki

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 127 KB

english, 2006

22

Reduction of gastrointestinal toxicity of NSAIDs via molecular modifications leading to antioxidant anti-inflammatory drugs

Panos N Kourounakis, Karyofyllis Tsiakitzis, Angeliki P Kourounakis, Dimitrios Galanakis

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 73 KB

english, 2000

23

Anti-inflammatory properties of diclofenac transition metalloelement complexes

Maria Konstandinidou, Angeliki Kourounakis, Minas Yiangou, Lygeri Hadjipetrou, Dimitra Kovala-Demertzi, Sotiris Hadjikakou, Mavroudis Demertzis

Journal:

Journal of Inorganic Biochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 128 KB

english, 1998

24

Synthesis and activity on free radical processes and inflammation of 9,10-dihydro-5,8-dimethoxy-triptycene-quinones

Nikoletta J Xanthopoulou, Angeliki P Kourounakis, Spyros Spyroudis, Panos N Kourounakis

Journal:

European Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 442 KB

english, 2003

25

Antioxidant Potential of Natural and Synthesised Polyprenylated Hydroquinones

Leto-A Tziveleka, Angeliki P Kourounakis, Panos N Kourounakis, Vassilios Roussis, Constantinos Vagias

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 136 KB

english, 2002

26

Quantitative Structure Activity Relationships of Catechol Derivatives on Nerve Growth Factor Secretion in L-M Cells

Angeliki Kourounakis, Nicholas Bodor

Journal:

Pharmaceutical Research

Année:

1995

Fichier:

PDF, 911 KB

1995

27

Synthesis and evaluation of a brain-targeted catechol derivative as a potential NGF-inducer

Angeliki Kourounakis, Nicholas Bodor, James Simpkins

Journal:

International Journal of Pharmaceutics

Année:

1996

Langue:

english

Fichier:

PDF, 1020 KB

english, 1996

28

Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis

Anna Tavridou, Loukas Kaklamanis, George Megaritis, Angeliki P. Kourounakis, Apostolos Papalois, Dimitris Roukounas, Eleni A. Rekka, Panos N. Kourounakis, Avgui Charalambous, Vangelis G. Manolopoulos

Journal:

European Journal of Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 418 KB

english, 2006

29

Differential effects of the allosteric enhancer (2-amino-4,5-dimethyl-trienyl)[3-(trifluoromethyl) phenyl]methanone (PD81,723) on agonist and antagonist binding and function at the human wild-type and a mutant (T277A) adenosine A1 receptor

Angeliki Kourounakis, Corine Visser, Miriam de Groote, Ad P. IJzerman

Journal:

Biochemical Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 233 KB

english, 2001

30

Allosteric modulation of G protein-coupled receptors

Ad IJzerman, Angeliki Kourounakis, Pieter van der Klein

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 80 KB

english, 2001

31

Synthesis and Evaluation of Brain-targeted Chemical Delivery Systems for the Neurotrophomodulator 4-Methylcatechol

ANGELIKI KOUROUNAKIS, NICHOLAS BODOR, JAMES SIMPKINS

Journal:

Journal of Pharmacy and Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 781 KB

english, 1997

32

Antioxidant Activity of Guaiazulene and Protection Against Paracetamol Hepatotoxicity in Rats

ANGELIKI P. KOUROUNAKIS, ELENI A. REKKA, PANOS N. KOUROUNAKIS

Journal:

Journal of Pharmacy and Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 466 KB

english, 1997

33

Novel Compounds Designed as Antistress Agents

Tsiakitzis, Karyophyllis C., Rekka, Eleni A., Kourounakis, Angeliki P., Kourounakis, Panos N.

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 697 KB

english, 2009

34

New Multifunctional Di- tert -butylphenoloctahydro(pyrido/benz)oxazine Derivatives with Antioxidant, Antihyperlipidemic, and Antidiabetic Action

Ladopoulou, Eleni, Matralis, Alexios N., Kourounakis, Angeliki P.

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2013

35

Novel Potent Inhibitors of Lipid Peroxidation with Protective Effects against Reperfusion Arrhythmias

Koufaki, Maria, Calogeropoulou, Theodora, Detsi, Anastasia, Roditis, Aristidis, Kourounakis, Angeliki P., Papazafiri, Panagiota, Tsiakitzis, Karyofyllis, Gaitanaki, Catherine, Beis, Isidoros, Kourouna

Journal:

Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 45 KB

english, 2001

36

Lipid-Lowering (Hetero)Aromatic Tetrahydro-1,4-Oxazine Derivatives with Antioxidant and Squalene Synthase Inhibitory Activity

Kourounakis, Angeliki P., Charitos, Christos, Rekka, Eleni A., Kourounakis, Panos N.

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 84 KB

english, 2008

37

Allosteric Modulation of the Adenosine A 1 Receptor. Synthesis and Biological Evaluation of Novel 2-Amino-3-benzoylthiophenes as Allosteric Enhancers of Agonist Binding †

van der Klein, Pieter A. M., Kourounakis, Angeliki P., IJzerman, Ad P.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 113 KB

english, 1999

38

Design of Novel Potent Antihyperlipidemic Agents with Antioxidant/Anti-inflammatory Properties: Exploiting Phenothiazine’s Strong Antioxidant Activity

Matralis, Alexios N., Kourounakis, Angeliki P.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2014

39

5‘- N -Substituted Carboxamidoadenosines as Agonists for Adenosine Receptors

de Zwart, Maarten, Kourounakis, Angeliki, Kooijman, Huub, Spek, Anthony L., Link, Regina, von Frijtag Drabbe Künzel, Jacobien K., IJzerman, Ad P.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 115 KB

english, 1999

40

Novel Benzoxazine and Benzothiazine Derivatives as Multifunctional Antihyperlipidemic Agents

Matralis, Alexios N., Katselou, Maria G., Nikitakis, Anastasios, Kourounakis, Angeliki P.

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.42 MB

english, 2011

41

Evaluation of two novel antioxidants with differential effects on curcumin-induced apoptosis in C2 skeletal myoblasts; involvement of JNKs

Peleli, Maria, Aggeli, Ioanna-Katerina, Matralis, Alexios N., Kourounakis, Angeliki P., Beis, Isidoros, Gaitanaki, Catherine

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2015

42

Synthesis of quinoline/naphthalene-containing azaphenothiazines and their potent in vitro antioxidant properties

Jeleń, Małgorzata, Bavavea, Eugenia I., Pappa, Maria, Kourounakis, Angeliki P., Morak-Młodawska, Beata, Pluta, Krystian

Journal:

Medicinal Chemistry Research

Année:

2015

Langue:

english

Fichier:

PDF, 628 KB

english, 2015

43

Synthesis, Antiretroviral and Antioxidant Evaluation of a Series of New Benzo[b]furan Derivatives

Varvaresou, Athanasia, Iakovou, Kriton, Filippatos, Evangelos, Souli, Charikleia, Calogeropoulou, Theodora, Ioannidou, Ioulia, Kourounakis, Angeliki, Pannecouque, Christophe, Witvrouw, Myriam, Padalko

Journal:

Arzneimittelforschung

Année:

2011

Langue:

english

Fichier:

PDF, 116 KB

english, 2011

44

Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution

Ladopoulou, Eleni M., Matralis, Alexios N., Nikitakis, Anastasios, Kourounakis, Angeliki P.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 820 KB

english, 2015

45

Antiatherosclerotic Properties of EP2302, a Novel Squalene Synthase Inhibitor, in the Cholesterol-fed Rabbit

Tavridou, Anna, Kaklamanis, Loukas, Papalois, Apostolos, Kourounakis, Angeliki P, Rekka, Eleni A, Kourounakis, Panos N, Charalambous, Avgui, Manolopoulos, Vangelis G

Journal:

Journal of Cardiovascular Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 645 KB

english, 2008

46

Synthesis of New Azulene Derivatives and Study of Their Effect on Lipid Peroxidation and Lipoxygenase Activity

Rekka, Eleni, Chrysselis, Michael, Siskou, Ioanna, Kourounakis, Angeliki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

2002

Langue:

english

Fichier:

PDF, 63 KB

english, 2002

47

Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity

Katselou, Maria G., Matralis, Alexios N., Kourounakis, Angeliki P.

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 716 KB

english, 2017

48

Effect of anti-inflammatory/antioxidant agent on diabetic hairless mouse skin

Deli, Eleni, Kyriazi, Maria, Dimakopoulou, Aggeliki, Karasmani, Marina, Giakoumaki, Maria, Grigoropoulos, Andreas, Anagnostou, Vassia, Kourounakis, Angeliki, Rallis, Michael

Journal:

Free Radical Biology and Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 52 KB

english, 2017

49

Optimizing the Pharmacological Profile of New Bifunctional Antihyperlipidemic/Antioxidant Morpholine Derivatives.

Matralis, Alexios N., Kourounakis, Angeliki P.

Journal:

ACS Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 276 KB

english, 2018

50

Morpholine as a privileged structure: A review on the medicinal chemistry and pharmacological activity of morpholine containing bioactive molecules

Kourounakis, Angeliki P., Xanthopoulos, Dimitrios, Tzara, Ariadni

Journal:

Medicinal Research Reviews

Année:

2019

Fichier:

PDF, 3.80 MB

2019